Hideaki Moriyama, Associate Professor
Department of Chemistry
29B Hamilton Hall
University of Nebraska-Lincoln
Lincoln, Nebraska 68588 United States
hideaki@unl.edu

Current Research:
Relationships between planetary-scale changes in the environment and biological adaptation are of important concern. The long-term goal of in my lab is to elucidate mechanisms of biological adaptation and to predict the future form of organisms through the atomic description of biological macromolecules. To approach this goal, we are proposing a concept of "temperature driven evolution," in which I try to organize information and to model the biological system along physical factors including temperature.

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2009

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N- and C-terminal domains in human holocarboxylase synthetase participate in substrate recognition, Yousef I. Hassan, Hideaki Moriyama, Lars J. Olsen, Xin Bi, and Janos Zempleni

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N- and C-terminal domains in human holocarboxylase synthetase participate in substrate recognition, Yousef I. Hassan, Hideaki Moriyama, Lars J. Olsen, Xin Bi, and Janos Zempleni

2008

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The MUT9p kinase phosphorylates histone H3 threonine 3 and is necessary for heritable epigenetic silencing in Chlamydomonas, Juan Casas-Mollano, Byeong-Ryool Jeong, Jianping Xu, Hideaki Moriyama, and Heriberto D. Cerutti

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Conserved sequences of sperm-activating peptide and its receptor throughout evolution, despite speciation in the sea star Asterias amurensis and closely related species, Mia Nakachi, Motonori Hoshi, Midori Matsumoto, and Hideaki Moriyama

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Identification of Guanylate Cyclases and Related Signaling Proteins in Sperm Tail from Sea Stars by Mass Spectrometry, Mia Nakachi, Midori Matsumoto, Philip M. Terry, Ronald L. Cerny, and Hideaki Moriyama

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Adaptive Functional Divergence among Triplicated α-Globin Genes in Rodents, Jay F. Storz, Federico G. Hoffmann, Juan C. Opazo, and Hideaki Moriyama

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Mechanisms of Hemoglobin Adaptation to High Altitude Hypoxia, Jay F. Storz and Hideaki Moriyama

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Mechanisms of Hemoglobin Adaptation to High Altitude Hypoxia, Jay F. Storz and Hideaki Moriyama

2007

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Purification, crystallization and preliminary crystallographic analysis of deoxyuridine triphosphate nucleotidohydrolase from Arabidopsis thaliana, Mamta Bajaj and Hideaki Moriyama

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Apparatus and Method for Growing Crystal, and Apparatus and Method for Analyzing Crystal: United States Patent No. 7,156,917 B2, Hideaki Moriyama, Norio Sugi, Kazunori Kawasaki, and Shoji Muramatsu

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Supporting Information for "The Molecular Basis of High-Altitude Adaptation in Deer Mice", Jay F. Storz, Stephen J. Sabatino, Federico G. Hoffmann, Eben J. Gering, Hideaki Moriyama, Nuno Ferrand, Bruno Monteiro, and Michael W. Nachman

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The Molecular Basis of High-Altitude Adaptation in Deer Mice, Jay F. Storz, Stephen J. Sabatino, Federico G. Hoffmann, Eben J. Gering, Hideaki Moriyama, Nuno Ferrand, Bruno Monteiro, and Michael W. Nachman

2006

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The Arabidopsis homolog of trithorax, ATX1, binds phosphatidylinositol 5-phosphate, and the two regulate a common set of target genes, Raul Alvarez-Venegas, Monther Sadder, Andrej Hlavacka, Frantisek Baluska, Yuannan Xia, Guoqing Lu, Alexey Firsov, Gautam Sarath, Hideaki Moriyama, Joseph G. Dubrovsky, and Zoya V. Avramova

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Acrosome reaction is subfamily specific in sea star fertilization, Mia Nakachi, Hideaki Moriyama, Motonori Hoshi, and Midori Matsumoto

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The Importance of the Strictly Conserved, C-terminal Glycine Residue in Phosphoenolpyruvate Carboxylase for Overall Catalysis: Mutagenesis and Truncation of Gly-961 in the Sorghum C4 Leaf Isoform, Wenxin Xu, Shaheen Ahmed, Hideaki Moriyama, and Raymond Chollet

2005

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Chlorella Virus-Encoded Deoxyuridine Triphosphatases Exhibit Different Temperature Optima, Yuanzheng Zhang, Hideaki Moriyama, Kohei Homma, and James L. Van Etten