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Information has pragmatic value for scientists for research and development. In the changing industrial climate in the North Eastern Region of India, institutes like North East Institute of Science and Technology (NEIST) play a significant role. NEIST is an R&D institute and a reservoir of technologies that have added to the rural development of the region. Working scientists spend one third of their time searching for information and the cost of this search represents one fifth of all the money allocated to science. Socio-economic development and technological progress depend on the effective use of the information generated in science and technology through R&D. This paper discusses information needs, use patterns, and constraints faced by the scientists of NEIST, Jorhat, including suggestions to solve problems.