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The anticoagulant rodenticide bromadiolone is used throughout the U.S. under a number of trade names. An expanded research program is underway within Chempar to examine the use of bromadiolone in commensal and field rodent control. Data are presented herein on the toxicology, metabolism, secondary hazards, efficacy, and formulation developments with bromadiolone. A new Maki 0.001% liquid bait is being tested and excellent control results obtained against Norway rats (Rattus norvegicus), roof rats (R. rattus), and house mice (Mus musculus). New Maki paraffin blocks containing 50 ppm bromadiolone have been developed and are soon to be on the market. Bromadiolone biogradability in the field and in animal tissues offers promise for expanded label claims for use in urban and field situations.