Date of this Version
Van Es, L., Olney, J.F., and Blore, I.C. (1946) Studies on the validity of swine erysipelas culture-vaccines (Research Bulletin: Bulletin of the Agricultural Experiment Station of Nebraska No. 145)
In countries where vaccination against swine erysipelas has been practiced during the last half century, there is a consensus among veterinarians that the best results are obtained when the live culture-vaccine is not only fresh and highly virulent but is endowed also with a good capacity for growth on artificial culture media. Apparently avirulent culture-vaccines are apt to engender only a transitory immunity or fail altogether. The problem presented by undesirable culture-vaccines was deemed to be of such importance to the swine industry that this Station undertook a series of experiments, to determine what influences might be accountable for the production of inferior vaccination materials.