Date of this Version
THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 288, NO. 28, pp. 20435–20442, July 12, 2013
Background: Host innate immunity is against virus infection and replication.
Results: Toll-like receptor 3 activation leads to enhanced expression of a key Kaposi’s sarcoma-associated herpesvirus (KSHV) protein.
Conclusion: KSHV uses host Toll-like receptor pathway to augment its critical gene expression. Significance: A virus may usurp host innate immunity for its own benefits.