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Teflubenzuron baits were active against laboratory colonies of the red imported fire ant, Solenopsis invicta Buren. Worker brood production ceased soon after treatment and by four weeks posttreatment, most colonies were devoid of brood. Worker ants did not exhibit any direct effects from treatment with teflubenzuron. As is typical with most insect growth regulators, colony mortality was slow and dependent on old- age attrition of the worker ants. A few (<25) female alates were produced in one of the laboratory colonies at 12 weeks posttreatment.