Outbreak of H7N8 Low Pathogenic Avian Influenza in Commercial Turkeys with Spontaneous Mutation to Highly Pathogenic Avian Influenza

Authors

Mary Lea Killian, U.S. Department of Agriculture (USDA), Ames, Iowa
Mia Kim Torchetti, US Department of Agriculture, Ames, IowaFollow
Nichole Hines, US Department of Agriculture, Ames, Iowa
Sam Yingst, Purdue University
Thomas J. Deliberto, USDA/APHIS/WS National Wildlife Research CenterFollow
Dong-Hun Lee, USDA Agriculture Research Service, Southeast Poultry Research Laboratory, Athens

Document Type

Article

Date of this Version

2016

Citation

Genome Announc 4(3):e00457-16.

doi:10.1128/genomeA.00457-16

Comments

US government work

Abstract

Highly pathogenic avian influenza (HPAI) subtype H7N8 was detected in commercial turkeys in January 2016. Control zone surveillance discovered a progenitor low pathogenic avian influenza (LPAI) virus in surrounding turkey flocks. Data analysis supports a single LPAI virus introduction followed by spontaneous mutation to HPAI on a single premises.