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The U.S. Department of Agriculture, Pesticide Regulation Division, has the responsibility of administering the Federal Insecticide, Fungicide and Rodenticide Act of 1947 as amended. The Act encompasses any substance or mixture of substances intended for "preventing, destroying, repelling or mitigating any insects, rodents or any other vertebrate animals, nematodes, fungi, weeds, and any other forms of plants or animal life or viruses," except viruses on or in living man or other animals. These products must be registered if they are to be marketed or shipped in interstate commerce, imported or exported, or sold in the District of Columbia or any of the territories. To obtain registration a manufacturer or formulator must submit an application, five copies of the proposed labeling, a complete statement of ingredients by percent, toxicity data, and adequate efficacy and safety data to the U.S. Department of Agriculture, Pesticides Regulation Division to support the petition. Such applications are reviewed by the appropriate scientific staffs of the Division to determine if the efficacy and safety data are adequate.