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A case of a credit bearing information literacy skills class, offered to first year undergraduate students though not across all colleges at the Kwame Nkrumah University of Science and Technology (KNUST), Ghana was analysed. The survey research methodology was used and questionnaire was distributed to 136 students. The findings indicated that the course was relevant and should be maintained though students’ knowledge on ethical use of information, citation skills, and information searching skills were poor. The study recommends a collaborative partnership between librarians and faculty for the teaching and learning of information literacy skills.