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The paper explores to what extent the Ayurvedic medical college library users are aware and use e-resources in their respective college library. The study is based on questionnaire distributed to the users of Ayurvedic medical college library with special reference to North Karnataka, India. The study found that library facilities are good in all the libraries under study. Tukey’s post hoc test reveals that the purpose of using e-resources varies from person to person. With regard to awareness of medical database, it is found that majority of the respondents do not aware of it. The statistical test results reveals that Medline plus is good and for other databases is unaware.