The study investigated the influence of work engagement on job burnout among librarians in university libraries in Nigeria. The study employed survey research design. The population of the study consisted of 624 librarians from 38 public universities in Southern Nigeria. Total enumeration was used. Data were analyzed using descriptive and inferential statistics. The findings revealed that work engagement significantly influenced job burnout of librarians in university libraries in Nigeria (β =.184, t(498) =4.191, R2 =.034, p<.05). The study concluded that work engagement contribute to low level of job burnout among librarians in universities in Nigeria and library management should maintain good work practice to prevent job burnout.