This paper reports on a study which assessed the effects of information and communication technology (ICT) on research and development activities at the Federal Institute of Industrial Research, Oshodi (FIIRO). The research focused on the use of computers, application software, and the Internet by all cadres of staff at the Institute. A thematic analysis highlighted the current state of ICT applications, level of literacy, and problems and challenges encountered in the application and use of ICTs. The study revealed a need to train members of staff in ICT. Infrastructure such as power supply and Internet connectivity need to be improved.