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The research sought to assess the effects of information literacy on administrative secretaries Ghana Ports and Harbor Authority and Electricity Company of Ghana both in Takoradi. The main purpose of this study is to determine the effects of information literacy on administrative secretaries of these two selected public organisations, kinds of digital equipment used in the organisation, and to determine if the administrative secretaries know how to use the digital equipment available to the organisation. The study assessed 158 staff population. The sample size was 60 staff. Out of 60 the targeted population, 36(54%) were from Ghana Ports and Harbor Authority, and 24(46%) were also from Electricity Company of Ghana both in Western Region, Takoradi, Ghana. The research design used was case study and stratified sample technique. Questionnaires were used as the research instrument with both open and closed ended questions for the objectives stated. Both primary and secondary data was also used. The work was analysed through coding using SPSS for displaying the collected questionnaires, frequency etc.