UCARE: Undergraduate Creative Activities & Research Experiences

 

Date of this Version

4-2016

Document Type

Poster

Citation

University of Nebraska-Lincoln, UCARE, Spring 2016 Research Fair Poster.

Comments

Copyright © 2016 Max Meier

Abstract

The purpose of this research is to synthesize a novel compound, 2,2,6,6-dispirocyclobutylpiperidine- 4-one (P), for use as an oxidation reactant to form the corresponding nitroxyl radical. This is to be conducted using a reliable method for a variety of 2,2,6,6-tetrasubstituted piperidine-4-one compounds as detailed by Sakai et al. [3]. Sakai uses a variety of 6-member cyclic ketones, which are quite stable. It was attempted to use 4-member cyclic ketones to research the effectiveness of 2,6-substitution using a less stable carbonyl compound. Cyclobutanone and 3-oxycetanone were used as candidates for this reaction. Both are delicate, expensive ketones.

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