Date of this Version
UCARE Poster session, University of Nebraska-Lincoln Research Fair, April 2016, Lincoln, NE.
We tested the hypothesis that a highfat diet would increase the difference in body weight between C57BL/6J mice provided dietary microRNA (Exo +) and mice which were fed the same diet depleted of microRNA (Exo-).
• The data demonstrate that depleting miRNAs from a high-fat diet does not impact the difference in body weight between Exo+ and Exo- subjects. • Depleting dietary miRNAs from normal low-fat diets do result in differences in body weight, fat, fecundity, purine metabolism, and gut microbiome.