Veterinary and Biomedical Sciences, Department of


Date of this Version

March 1981


Although it has been clearly demonstrated that antibodies to pneumococcal capsules are protective in both mice and men (1, 2), the protective properties of antibodies to other pneumococcal constituents have been less well investigated. In the present report we describe results indicating that naturally occurring antibodies binding with the phosphocholine (PC) determinant of the pneumococcal cell wall C-carbohydrate (3) are important in the protection of mice from experimental pneumococcal infections.