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Both high- and low-HCN-p genotypes of sorghum, Sorghum bicolor (L) Moench, were resistant to the European com borer (ECB), Ostrinia nubilalis (Hübner). It was not proven that HCN-p is or is not a chemical factor conditioning resistance to leaf feeding by first-generation ECB and resistance to sheath-collar feeding by second-generation ECB in sorghum. If HCN-p is a resistance factor, however, it is effective at very low levels because levels in the low-HCN-p genotypes were very low. DIMBOA is not a chemical factor conditioning resistance in sorghum to the ECB because midwhorl leaves and sheath-collar tissue of both high- and low-HCN-p genotypes contained no DIMBOA.