Date of this Version
Van Es, L. and Martin, H.M. (1920) The immunizing value of commercial vaccines and bacterins against hemorrhagic septicemia (Research Bulletin: Bulletin of the Agricultural Experiment Station of Nebraska No. 17)
In the course of certain studies having to do with hemorrhagic septicemia, we were particularly struck with the difficulties which we encountered in the immunization of susceptible laboratory animals (rabbits). This difficulty in no small degree excited our curiosity regarding the immunizing value of the considerable number of "Hemorrhagic Septicemia bacterins and vaccines" which during recent years have become such a prominent article of commerce. In the hope of securing some information relative to the immunizing value of the agents mentioned, we undertook a series of experiments in which the immunity of the bacterin and vaccine injected laboratory animals was definitely tested by subsequent inoculations with B. bipolaris.