Simulation Supported Estimation of End-to-End Transmission Parameters in Non-Viral Gene Delivery

Authors

Beata J. Wysocki, University of Nebraska-LincolnFollow
Tadeusz A. Wysocki, University of Nebraska-LincolnFollow
Timothy M. Martin, University of Nebraska-LincolnFollow
Angela K. Pannier, University of Nebraska-LincolnFollow

Document Type

Article

Date of this Version

2014

Citation

Published in: 2014 IEEE International Conference on Communications (ICC), 10-14 June 2014, Sydney, NSW, pp 4179-4183.

Comments

©2014 IEEE. Used by permission.

Abstract

Communications, in general, involve delivery of information from a source to a sink. At nano-scale, an example of a man-made communications involving interfacing with biological systems at intra-cellular level is non-viral gene delivery. From a telecommunications engineering perspective, important end-to-end parameters of such a system are: the endto- end delay, system capacity, and packet loss rate. There are neither known methods to estimate those parameters theoretically nor they are ready available from standard measurements. The paper provides estimates for those parameters based on the simulation of non-viral gene delivery system based on the queuing theory. The simulator used has been validated through the series of in-vitro laboratory experiments.