Depression and the Long-Term Risk of Pain, Fatigue, and Disability in Patients with Rheumatoid Arthritis

Authors

Judith Fifield, University of Connecticut School of Medicine, Farmington, CT
Howard Tennen, University of Connecticut School of Medicine, Farmington, CT
Susan Reisine, University of Connecticut School of Dental Medicine, Farmington, CT
Julia McQuillan, University of Nebraska - LincolnFollow

Date of this Version

October 1998

Comments

Published in Arthritis & Rheumatism 41:10 (October 1998), pp. 1851-1857. Copyright © 1998 American College of Rheumatology. Published by John Wiley & Sons. Used by permission. http://www3.interscience.wiley.com/journal/76509746/home

Abstract

Objective. To determine whether a previous episode of major depression leaves a “scar” that places previously depressed patients with rheumatoid arthritis (RA) at risk for experiencing high levels of pain, fatigue, and disability.

Methods. A cohort of 203 patients with RA was randomly selected from a national panel and interviewed by phone about pain, fatigue, depressive symptoms, disability, and history of major depression.

Results. Excluding patients who met the criteria for current major depression, patients with both a history of depression and many depressive symptoms at the time of the interview (dysphoria) reported more pain than those without current dysphoria, irrespective of whether they had a history of depression. Dysphoria alone was not reliably related to pain reports.

Conclusion. An episode of major depression, even if it occurs prior to the onset of RA, leaves patients at risk for higher levels of pain when depressive symptoms persist, even years after the depressive episode.