Novel approach for synthesis of 2:1 Permethylated β-cyclodextrin–C₆₀ Conjugate

Authors

Zhu Guan, Université Pierre et Marie Curie, Paris
Yali Wang, University of Nebraska-LincolnFollow
Yong Chen, Université Pierre et Marie Curie, Paris
Yongmin Zhang, Université Pierre et Marie Curie, ParisFollow

Date of this Version

2008

Document Type

Article

Citation

Tetrahedron (February 7, 2009) 65(6): 1,125–1,129

doi: 10.1016/j.tet.2008.12.001

Comments

Copyright © 2008, Elsevier. Used by permission

Abstract

Amphiphilic cyclodextrin–fullerene conjugates have potential biological activity, due to their water solubility. In order to study the influence of the linker of these conjugates on solubility and aggregation, a permethylated β-cyclodextrin–C₆₀ conjugate with a short linker –(CH₂)₂NHCO–, which is attached to the secondary face of β-cyclodextrin was synthesized. Its solubility in water and its UV spectrum in CH₂Cl₂ and water were investigated.