A Mild One-Pot Conversion of Alkenes into Amines through Tandem Ozonolysis and Reductive Amination

Authors

ShivaKumar Kyasa, University of Nebraska–LincolnFollow
Thomas J. Fisher, University of Nebraska–Lincoln,Follow
Patrick Dussault, University of Nebraska-LincolnFollow

Date of this Version

11-2011

Comments

Published in Synthesis 21 (2011), pp. 3475–3481; doi: 10.1055/s-0030-1260244 Copyright © 2011 Georg Thieme Verlag, Stuttgart & New York. Used by permission.

Abstract

The selective reduction of hydroperoxyacetals to aldehydes by sodium triacetoxyborohydride provides the basis for a mild one-pot synthesis of amines from alkenes.

Includes Supplementary Materials.