Department of Chemistry

 

Document Type

Article

Date of this Version

2011

Citation

ACS Med Chem Lett. 2011 Apr 14; 2(4): 316–319.

Comments

Copyright © 2011 American Chemical Society

Abstract

A number of 3-alkoxy-1,2-dioxolanes exhibit promising levels of antimalarial activity against Plasmodium falciparum. A new route to the 1,2-dioxolane core is reported based on tandem peroxidation/cyclization of enones.

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