B(C₆F₅)₃-promoted tandem silylation and intramolecular hydrosilylation: diastereoselective synthesis of oxasilinanes and oxasilepanes

Authors

Roman Shchepin, University of Nebraska–Lincoln
Chunping Xu, University of Nebraska-Lincoln
Patrick Dussault, University of Nebraska-LincolnFollow

Date of this Version

2010

Citation

Org Lett. 2010 November 5; 12(21): 4772–4775.

Comments

Copyright © 2010 American Chemical Society

Abstract

B(C₆F₅)₃ promotes regio- and stereoselective cyclizations of unsaturated alkoxysilanes to generate oxasilinanes and oxasilepanes. The same products are available directly from alkenols via tandem silylation and hydrosilylation.