Electrical & Computer Engineering, Department of

 

ORCID IDs

Hasan H. Otu

Document Type

Article

Date of this Version

2010

Citation

BMC Genomics 2010, 11:342

Comments

© 2010 Bhasin et al

Open access

doi:10.1186/1471-2164-11-342

Abstract

Background: In this study, we used a systematic bioinformatics analysis approach to elucidate genes that exhibit an endothelial cell (EC) restricted expression pattern, and began to define their regulation, tissue distribution, and potential biological role.

Results:Using a high throughput microarray platform, a primary set of 1,191 transcripts that are enriched in different primary ECs compared to non-ECs was identified (LCB >3, FDR

Conclusion: The study provides an initial catalogue of EC-restricted genes most of which are ubiquitously expressed in different endothelial cells.

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