Date of this Version
Basic knowledge of the nutritional and hormonal requirements for normal development of the fetus and other gravid uterine tissues is essential to establish bases from which to study factors that my contribute to abnormal fetal development. Despite recognition of this necessity, few data are available that describe blood flow to the gravid uterus of cows. Data obtained by Ferrell and Ford (1980) indicated blood flow to the gravid uterus was 75, 155, 154, 105, and 60 ml/min/kg at 80, 140, 180, 210, and 240 days of gestation. Silver and Comline (1975) reported blood flow to be 312±20 ml/min/kg gravid uterus in cows during late gestation. Blood flow to the gravid uterus in cows was about 14% of cardiac output, which compares favorably to the estimate of 15.7% in sheep. The estimate obtained by Solver and Comline would represent about 35% of cardiac output. It is probable that the estimates of Ferrell and Ford (1980) were underestimates and those of Silver and Comline (1975) were overestimates of uterine blood flow.