MECHANICAL PERFORMANCE OF PLLA STENT

Authors

Longzhen Wang, University of Nebraska-LincolnFollow
Junfei Tong, University of Nebraska-LincolnFollow
Pengfei Dong, University of Nebraska-LincolnFollow
David L. Wilson, Case Western Reserve University
Hiram G. Bezerra, UH Cleveland Medical Center
Linxia Gu, University of Nebraska-LincolnFollow

Date of this Version

2018

Citation

2018 Des Med Devices Conf (2018). 2018 April ; 2018

Comments

Copyright 2018 by ASME

doi:10.1115/DMD2018-6957

Abstract

Stent implantation is widely used to treat blocked lumen. Stents were meshed structure made of polymers and metal alloys, including stainless steel, cobalt chrome and nitinol [1]. Clinical studies had demonstrated that stents helped to scaffold the diseased lesion up to one year when tissue adapted to the stented environment [2]. However, the permanently implanted stents inside artery were associated with complications such as stent fracture, tissue inflammation, in-stent restenosis and thrombosis [3]. Currently, biodegradable stents are attracting more attention due to its potential long-term efficacy in treating blocked lumens. The detailed characterizations of biodegradable stents are essential for the desired clinical outcomes.

In this work, the mechanical performance of Absorb GTI™ Bioresorbable stent made of PLLA (Poly-L-Lactide Acid) was studied using finite element method (FEM). Both the stent crimping and deployment were quantified towards the optimization of its scaffolding capacity in a limited time.