Association of Diet QualityMeasured by Three A Priori-Defined Dietary Patterns With Gut Microbiota and Intestinal Permeability Among Obese Individuals

Authors

Sarah Eaton, University of Nebraska-Lincoln
Heather Rasmussen, University of Nebraska - LincolnFollow
Weiwen Chai, University of Nebraska - LincolnFollow

Date of this Version

2022

Citation

Curr Dev Nutr. 2022 Jun; 6(Suppl 1): 361. Published online 2022 Jun 14.

doi: 10.1093/cdn/nzac054.016

PMCID: PMC9193795

Abstract

Objectives: The human gastrointestinal tract (GI)may play a critical role in the prevention of obesity and metabolic diseases. Considering the importance of a healthy diet for optimal health, this study examined associations of diet quality assessed by three a priori-defined dietary patterns (Healthy Eating Index 2010 [HEI-2010],Mediterranean Eating Pattern for Americans [MEPA], and Dietary Approaches to Stop Hypertension [DASH] with gut microbiota, short-chain fatty acids (SCFA) and intestinal permeabilitymarkers in adult obese participants.

Conclusions: Blautia abundance and inversely associated with intestinal permeability markers such as urinary 24-h sucralose levels suggesting diet quality may have positive impact on the human GI community.