Track Theory Predictions for Single-Hit Cell Survival

Authors

• Robert Katz, University of Nebraska-LincolnFollow
• Francis Cucinotta, NASA Johnson Space CenterFollow

Document Type

Article

Date of this Version

2000

Comments

Published in RADIATION RESEARCH 153, 220–238 (2000).

Abstract

The track theory of cell survival after heavy-ion irradiation is based on the probability of survival after a single-particle transit, called ‘‘ion-kill’’ (not track core), joined to the cumulative effect of δ rays from adjacent ions in a beam, called ‘‘gamma-kill’’ (not penumbra). The model offers a set of equations containing four parameters, E₀ and m for the single-hit multitarget statistical model for gamma-kill, and additionally σ₀ and κ for ion-kill. A single set of parameters is used to fit a family of survival curves obtained with ions of different LET simultaneously.