DNA MOLECULES AND POLYPEPTIDES OF PSEUDOMONAS SIRINGAE HRP PATHOGENICITY ISLAND AND THEIR USES: U.S. Patent No. US 6,852,835 B2

Authors

Alan Collmer, Cornell UniversityFollow
James R. Alfano, University of Nebraska-LincolnFollow
Amy O. Charkowski, University of Wisconsin - MadisonFollow

Document Type

Article

Date of this Version

2-8-2005

Comments

United States Patent NO.: US 6,852,835 B2
Collmer et al.
Date of Patent: Feb. 8, 2005

Abstract

One aspect of the present invention relates to isolated nucleic acid molecules (i) encoding proteins or polypeptides of Pseudomonas CEL and EEL genomic regions, (ii) nucleic acid molecules which hybridize thereto under stringent conditions, or (iii) nucleic acid molecules that include a nucleotide sequence which is complementary to the nucleic acid molecules of (i) and (ii). Expression vectors, host cells, and transgenic plants which include the DNA molecules of the present invention are also disclosed. Another aspect relates to the isolated proteins or polypeptides and compositions containing the same. The nucleic acid molecules and proteins of the present invention can be used to imparting disease resistance to a plant, making a plant hypersusceptible to colonization by nonpathogenic bacteria, causing eukaryotic cell death, and treating cancerous conditions.