Mammalian Pathogenesis and Transmission of Avian Influenza A(H7N9) Viruses, Tennessee, USA, 2017

Authors

Jessica A. Belser, CDC
Nicole Brock
Xiangjie Sun
Joyce Jones
Natosha Zanders
Erin Hodges
Joanna A. Pulit-Penaloza
David Wentworth
Terrence M. Tumpey
Todd Davis
Taronna R. Maines, CDCFollow

Date of this Version

2018

Citation

Emerging Infectious Diseases Vol. 24, No. 1, January 2018

Comments

This document is a U.S. government work and is not subject to copyright in the United States.

DOI: https://doi.org/10.3201/eid2401.171574

Abstract

Infections with low pathogenicity and highly pathogenic avian influenza A(H7N9) viruses affected poultry in 4 states in the southeastern United States in 2017. We evaluated pathogenicity and transmission of representative viruses in mouse and ferret models and examined replication kinetics in human respiratory tract cells. These viruses can cause respiratory infections in mammalian models.