Direct Involvement of Type II Secretion System in Extracellular Translocation of Shewanella oneidensis Outer Membrane Cytochromes MtrC and OmcA

Authors

Liang Shi, Pacific Northwest National LaboratoryFollow
Shuang Deng, Pacific Northwest National Laboratory
Matthew Marshall, Pacific Northwest National Laboratory
Zheming Wang, Pacific Northwest National LaboratoryFollow
David Kennedy, Pacific Northwest National LaboratoryFollow
Alice Dohnalkova, Pacific Northwest National LaboratoryFollow
Heather Mottaz, Pacific Northwest National Laboratory
Eric Hill, Pacific Northwest National Laboratory
Yuri Gorby, J. Craig Venter Institute
Alexander Beliaev, Pacific Northwest National LaboratoryFollow
David Richardson, University of East AngliaFollow
John M. Zachara, Pacific Northwest National LaboratoryFollow
James K. Fredrickson, Pacific Northwest National LaboratoryFollow

Date of this Version

2008

Citation

JOURNAL OF BACTERIOLOGY, Aug. 2008, p. 5512–5516 Vol. 190, No. 15; doi:10.1128/JB.00514-08

Abstract

MtrC and OmcA are cell surface-exposed lipoproteins important for reducing solid metal oxides. Deletions of type II secretion system (T2SS) genes reduced their extracellular release and their accessibility to the proteinase K treatment, demonstrating the direct involvement of T2SS in translocation of MtrC and OmcA to the bacterial cell surface.