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Thesis (M.S.)—University of Nebraska—Lincoln, 1929. Department of Chemistry.


Copyright 1929, the author. Used by permission.


The conversion of one aldose into another aldose and several ketoses slowly by weak alkalis at ordinary temperatures and quickly with much decomposition at elevated temperatures, was first observed by Lobry de Bruyn and later investigated by Nef and his students in an elaborate study on the action of strong alkalis alone and with oxidizing agents extending over a period of ten years. The results of these studies on oxidation were interpreted as depending on the presence of several intermediate enediols. The oxidation of sugars in approximately six normal alkali medium with air or oxidizing agents all give about the same general results in regard to the sugar destroyed, non-volatile and volatile acids produced. In these oxidations the concentration of the –OH ion decreases as the reaction proceeds. To the present time but one study on the products of oxidation of the simple sugars in an alkaline solution having a fairly constant –OH ion concentration has been reported; that of Powers using lime water. In this work the oxidation products only were studied and not the rate of oxidation. The present work was started to study the rate of such an oxidation, because of the animal oxidation where the body maintains exacting degrees of acidity and alkalinity.

Advisor: F. W. Upson