Date of this Version


Document Type



Lawson, Donald E. and Ball, Harold J. (1969) Effects of metepa on gametogenesis and embryogenesis in the large milkweed bug Oncopeltus fasciatus (Dallas) (Research Bulletin: Bulletin of the Agricultural Experiment Station of Nebraska No. 234)


ISSN 0097-1565


Considerable research is currently being directed toward discovering means of controlling insects other than by applying insecticides. There are several promising concepts of control which minimize the use of insecticides and one of these is the use of sterilizing techniques. Some emphasis is currently being placed on the development of chemosterilant techniques. Many of the studies have been concerned with the screening of potentially active chemicals, whereas other research has dealt with the efficacy of field application. The more basic work has been accomplished through the participation of several disciplines. The purpose of this study was to characterize the effects and mode of action of a particular chemosterilant, metepa (tris [1-(2 methyl) aziridinyl] phosphine oxide) on the large milkweed bug, Oncopeltus fasciatus (Dallas). Attention was given to determination of the locus of attack and the relationship of dosage to effects on tissue from both embryonic and reproductive sources. The effects of dosage level on egg viability and female fecundity were also studied.