Papers in the Biological Sciences


Complete Genome Sequence of an Evolved Thermotoga maritima Isolate

Raghuveer Singh, University of Nebraska - Lincoln
Julien Gradnigo, University of Nebraska - Lincoln
Derrick White, University of Nebraska - Lincoln
Anna Lipzen, U.S. Department of Energy-Joint Genome Institute
Joel Martin, U.S. Department of Energy-Joint Genome Institute

Copyright © 2015 Singh et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license.


Thermotoga maritima is a hyperthermophilic bacterium with a small genome (1.86 Mbp). Genome resequencing of Tma200, a derivative produced by experimental microbial evolution, revealed the occurrence of deletions and substitution mutations. Their identification contributes to a better understanding of genome instability in this organism.