Chemical and Biomolecular Engineering, Department of

 

Date of this Version

2007

Document Type

Article

Citation

Patent No.: US 7,220,718 B2

Comments

Appl. No.: 10/485,696

Abstract

Disclosed herein is a simple method for the treatment of antigen-deficiency diseases, by orally administering to a subject a therapeutically effective amount of the deficient antigen, wherein the antigen is not present in a liposome. In one embodiment, the method increases hemostasis in a subject having hemophilia A or B, by orally administering to the hemophiliac a therapeutically effective amount of the appropriate clotting factor other than in a liposome, sufficient to induce oral tolerance and supply exogenous clotting factor to the subject.

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