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Foot and mouth disease (FMD) is an extremely contagious viral disease of cloven-hooved animals such as cattle, pigs, sheep, and deer. The disease is not commonly fatal, but causes extreme production losses in affected herds. Clinical signs of the disease include lameness, excessive salivation, reluctance to eat, abortion and blister-like erosions on the mouth and feet. Affected animals are debilitated and may not recover to their original production levels. The disease has long been recognized as one of the most economically devastating diseases of livestock.