First Complete Genome Sequence of a Genotype A2, Subgroup 4 Small Ruminant Lentivirus

Authors

Aspen M. Workman, USDA, ARS, U.S. Meat Animal Research CenterFollow
Michael L. Clawson, USDA, ARS, U.S. Meat Animal Research CenterFollow
Michael P. Heaton, USDA, ARS, U.S. Meat Animal Research CenterFollow
Aaron M. Dickey, USDA, ARS, U.S. Meat Animal Research CenterFollow

ORCID IDs

https://orcid.org/0000-0003-2852-3519

Date of this Version

11-15-2018

Document Type

Article

Citation

Workman AM, Clawson ML, Heaton MP, Dickey AM. 2018. First complete genome sequence of a genotype A2, subgroup 4 small ruminant lentivirus. Microbiol Resour Announc 7:e01337-18. https://doi.org/10.1128/MRA .01337-18.

Comments

Workman et al. Volume 7 Issue 19 e01337-18

Abstract

Genetic variation in the ovine TMEM154 gene associates with susceptibility to small ruminant lentivirus (SRLV) infection. We report here the first complete genome sequence for a genotype A2, subgroup 4 SRLV isolated from a Hampshire ewe with two copies of a TMEM154 frameshift mutation predicted to abolish protein function.