U.S. Department of Agriculture: Animal and Plant Health Inspection Service


Date of this Version



In Erica Spackman (ed.), Animal Influenza Virus: Methods and Protocols, Methods in Molecular Biology, vol. 2123, https://doi.org/10.1007/978-1-0716-0346-8_32


US govt


During recent years, serological evidence has shown that a number of peridomestic mammals (e.g., those commonly found in or around human structures) are naturally exposed to influenza A viruses (IAVs). In addition, experimental studies have demonstrated that many of these species can successfully replicate several different IAVs, including IAVs of high consequence to public or agricultural health. The replication of some IAVs within this group of mammals could have implications for biosecurity associated with poultry production and live bird markets in some regions of the world. Given this evidence, the need for further study and understanding of the role that peridomestic mammals may play in IAV dynamics is increasingly being recognized. This chapter will provide a general overview on IAV associations in peridomestic mammals, especially as they pertain to avian IAVs, and provide some general views and guidelines for sampling these species in various situations.