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One of the most successful immunocontraceptive vaccines used for wildlife is porcine zona pellucida (PZP). Several authors have published on the use of PZP immunocontraceptive vaccines to immunosterilize white-tailed deer. This is the first long term study of the use of GnRH contraception of deer. This GnRH immunocontraceptive study was part of a multi-year White- Tailed deer infertility study on the deer herd at Pennsylvania State University, (PSU) University Park, Pennsylvania in cooperation with National Wildlife Research Center, (NWRC) Fort Collins, CO.