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To test heuristic algorithms and techniques, researchers need numerous datasets so as to measure effectiveness and improve approaches. This paper discusses using Mathematica, a mathematical programming language, for randomly generating the specifications for manufacturing flow line models. Important issues include determining an arrival rate to a flow line, the number of flow line stations, the number of parallel servers for each production station, and specifying the service time distributions and their associated parameters. The paper concludes with a discussion on generating more general types of simulation models.