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Nigeria the most populous country in Africa with a population of about 180 million people is not ruled out of countries facing and suffering under the dangerous claws of HIVAIDS. Owing to this, there came the need to get the masses more sensitised on how to curb the spread of the disease and if possible obliterate the disease from the among students in tertiary institutions. A descriptive survey research design was used for this study. The study population consisted of ninety (90) undergraduates’ students within six (6) Faculties of Adeleke University, Ede, Osun State Nigeria and simple random technique was used to select for the study. Instrument of data collection was a questionnaire. Prior to the administration of the instrument, draft copies were administered to select undergraduates of Redeemers University, Ede and all observations and revision of the instrument were effected. Data collected from the study were analysed using SPSS. The study concluded that the media and the university has contributed significantly to students’ knowledge about causes, mode of transmission and prevention of HIV/AIDS through its various health programmes such as provision of HIV/AIDS policy. Besides it was also found out that parents before they their admission to the university. The study recommends that universities should continue to provide adequate HIV/AIDS information to students with a view to helping the reduction or elimination of the transmission of the deadly disease amongst undergraduate students.