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ABSTRACT: The present study analyses the research output of the Indian Institute of Toxicology Research (IITR) for the period of 25 years (1993 to 2017). The study emphasizes on the various characteristics of the publications such as highly cited papers, national & international collaboration profile, Degree of Collaboration, most prolific authors, most preferred journals for communication, citation impact of the publications, most frequently used author keywords. The Web of Science, a multidisciplinary bibliographic database was used to retrieve the data for the study. The scientists of IITR preferred to publish in the foreign journals. No journal in which the research works of IITR scientists were published belonged to India. 5.73% of the total publications remained uncited. Only 0.86% of the total publications were contributed by the single authors and rest of the 99% publications were contributed by multi-authors in collaboration. The 13% of the total publications were internationally collaborated and 86% of them were domestically collaborated. The Oxidative Stress, Apoptosis, DNA Damage and Lipid Peroxidation were found to be the most active research areas as per the analysis of keywords of authors.