The main purpose of the study was to examine the influence of Collection Development Policy and User Satisfaction in University Libraries in Rivers State, Nigeria. Three research questions and three research hypotheses were formulated to guide the study. The study adopted a descriptive research design using questionnaire as major instrument for eliciting data. The questionnaire titled (CDPIUSUL) was used for this purpose. A total number of 65 staff constituted the population. The population was purposively adopted because of the smaller size, comprising of 33 for Ignatius Ajuru University of Education and 32 for Rivers State University (RSU) respectively. All copies of questionnaire, distributed were completed and returned. Mean and standard deviation was used to answer research questions while independent t-test was used to test the null hypotheses. The study revealed that there is a significant influence of collection development policies on users’ satisfaction based on knowledge of collection development policy, availability of current resources and evaluation of collection development policy. Based on the findings, it was recommended that librarians should always make use of the CDP to guide in the selection of relevant materials to ensure users’ satisfaction. University authorities should ensure that there is regular evaluation of collections development policies to guide weeding in the libraries and Government should partner with the University management to always donate and acquire current information resources to the libraries in order to enhance users’ satisfaction.