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The pilot study investigated the integration of information communication and technology (ICT) with library instruction in Clifford University Owerrinta, Abia State, Nigeria. The emergence of ICT as a tool for teaching and learning and its acceptance in all human endeavours has increased the need for the modification of the methods that are currently been used in the delivery of library instruction in most universities in Nigeria. The study was a pre and post type using a total enumeration method with a population of 124 first year students of 2016/2017 academic session. Two instruments were developed and validated by two professors in the field of Library and Information Science from the Imo State University, Owerri with a reliability result of 0.82 and 0.84 respectively using Cronbach alpha procedure. The instruments were administered face-to-face on the same respondents who registered for Library Instruction course in the first and second semesters with 100% participation. The finding revealed that a modification on the current traditional methods of library instruction adopted in some Nigeria universities for an inclusive method adjoining ICTs would have a positive effect on the students’ academic career. It showed a significant improvement in the use of ICT tools and facilities in research among the respondents. Findings showed a major improvement by integrating ICT with library instruction among the respondents in searching for information on the Internet, e-databases and OPAC; retrieving and downloading of information from the Internet, and preparation of presentations using MS Power-point. Findings further revealed inadequate ICT facilities in the library and lack of personal ICT tools for students such as laptops as major setbacks for integrating ICT with library instruction. The study recommended a full integration of ICT-based courses with library instruction and provision of ICT tools such as projector, interactive board, computers, laptops and good Internet connection as a means of achieving result-oriented approach of library instruction programme in Nigerian universities.