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The paper analyses the growth pattern of Lupus disease literature during 2010-2017. The data downloaded from web of science database, further interpreted and analyzed for the study purpose. Total number of publications has been identified as 38750 records. The distribution of publications based on the year of production, country wise productivity, document type of the publications, Major subject categories, Authors whose contribution is in the maximum level were studied. The study reveals a progressive increase on LUPUS research during 2010-2017. The year 2016 contributed highest number of publications. United States is the top contributor during 2010-2017. PETRI M is the leading author having 394 articles which is 1.017% of the total publications.