The study investigated Screening, Interviews, Selection Processes and Its Effects on job Performance of librarians in federal university libraries in South-South, Nigeria. The study adopted the correlation research design. Four (4) research questions and three (3) hypotheses guided the study. The population of the study comprised 108 academic librarians in the six Federal universities spread across the six states of South-South, Nigeria. The entire 108 questionnaires was administered to the respondents, only 95 was filled and returned, and was used for the study because the entire population size was manageable. The overall reliability of the instrument yielded 0.95 with the use of Cronbach Alpha Coefficient. The rating scale of 4 points was subjected to an estimation procedure using SPSS version 17.0. A mean score of 2.5 and above on any item was accepted. Pearson r and R2 was used to answer the research questions while the null hypotheses were tested with the use of linear regression analysis. The major findings of the study were that the extent on the screening process used for recruitment of librarians was moderately high; the interview method used for the recruitment of librarians were rated moderately high; the selection criteria adopted for the recruitment of librarians was high. Based on the findings, it was recommended as follows: Screening of suitable librarians should be carried out diligently; The interview method should not be biased; Selection of qualified librarians should be done according to the laid down procedures.