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Using the Science Citation Index-Expanded of the Web of Science Core Collection, we analyzed global saffron research literature published between 1991 and 2017. The variables examined were research performance of nations, institutions, and authors. The study noted that the distribution of author keywords, citations, and publication patterns of saffron related articles to ascertain the research inclinations. The highly cited articles and author keyword analysis showed that the chemical and biochemical qualities of saffron were of key interest for the researchers.