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The study examined 2053 papers related to the publications of SAARC Countries on Colorectal cancer indexed in the web of science databases during 2010- 2018. The world colorectal cancer output (116203 publications) was formed from several countries. The present study analyzed the research output, authorship pattern, collaborative pattern, and activity index of five SAARC Countries viz. India, Pakistan, Bangladesh, Sri Lanka, and Nepal. The study revealed that India is a leading country among the five SAARC Countries with major research contributions. India’s continuous collaboration with other developed countries shows a higher activity index particularly in the context of individual research productivity. Developed countries like the USA, Australia, and the UK are the top collaborating countries with SAARC regions.