The university education system aims to preserve and enhance human knowledge by strengthening the research abilities of students, resulting in the promotion of independent learning. These goals cannot be achieved without the help and intervention of an information specialist, as well as faculty. Knowledgeable navigators (e.g. librarians and lecturers) have to locate and evaluate information before passing it on to their students for use. This study sought to examine the link between information literacy skills (ILS) and library patronage. A questionnaire survey was used to collect data from 120 faculty members at the University of Health and Allied Sciences in Ho, Ghana. This method was used because of its potential for generalising findings to a larger population. The Statistical Package for Social Science (SPSS) version 21 was used to analyse the data into frequencies and percentages. Findings revealed that respondents mostly use the library to access print materials. It was revealed that while faculty do have information literacy skills, continuous training is necessary to keep up with the changing information environment. As a result, management is encouraged to provide academic librarians with the necessary resources to present periodic seminars and training on searching strategies.